Arc Institute & NVIDIA AI Releases: Evo 2

arcinstitute.org ↗

ThursdAI — the weekly AI news podcast hosted by Alex Volkov — has covered one Arc Institute & NVIDIA release so far: Evo 2 on Feb 20, 2025. Arc Institute and NVIDIA release Evo 2, a 40B state-of-the-art genomics model. The entry below has primary-source links and the episode where we covered it live.

1 release1 open weight1 episodecovered Feb 20, 2025

February 2025 1

Arc Institute & NVIDIA
New ModelsOpen weights

Evo 2

Arc Institute and NVIDIA release Evo 2, a 40B state-of-the-art genomics model

Arc Institute and NVIDIA introduced Evo 2, a state-of-the-art genomics model with around 40 billion parameters trained on 9.3 trillion nucleotides. It uses the StripedHyena architecture to process genetic sequences up to 1 million nucleotides, enabling prediction of genetic mutation effects and even design of entire genomes. Fully open: two papers, weights, data, and training and inference codebases.